Basic Information
Symbol
circLRP1B
RNA Class
circRNA
Alias
LDL Receptor Related Protein 1B
LRP-DIT
LRPDIT
Low Density Lipoprotein Receptor-Related Protein 1B
Low-Density Lipoprotein Receptor-Related Protein 1B
LRP-Deleted In Tumors
LRP-1B
Low Density Lipoprotein Receptor Related Protein-Deleted In Tumor
Low-Density Lipoprotein Receptor-Related Protein-Deleted In Tumor
Low Density Lipoprotein-Related Protein 1B (Deleted In Tumors)
EC 3.4.21.9
EC 1.1.1.94
Location (GRCh37)
2:140989360-142889270
UCSC Genome Browser
Location (GRCh38)
2:140231791-142131701
Host gene
LRP1B
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr2_0151700 | Intergenic-Intergenic | chr2:142536460-142537845 | chr2:141778891-141780276 | 1386 nt | 0.3319 |
| hsa_LRP1B_0043000 | Intron-Intron | chr2:142549210-142549665 | chr2:141791641-141792096 | 456 nt | 0.3794 |
| hsa_LRP1B_0043300 | Intron-Exon-Intron | chr2:142567848-142573476 | chr2:141810279-141815907 | 250 nt | 0.4040 |
| hsa_LRP1B_0043400 | Intron-Exon-Intron | chr2:142567848-142573669 | chr2:141810279-141816100 | 250 nt | 0.3360 |
| hsa_LRP1B_0043600 | Intron-Exon-Intron | chr2:142567848-142705840 | chr2:141810279-141948271 | 520 nt | 0.4865 |
| hsa_LRP1B_0043500 | Intron-Exon-Intron | chr2:142567848-142731221 | chr2:141810279-141973652 | 250 nt | 0.3560 |
| hsa_LRP1B_0043700 | Intron-Intron | chr2:142615512-142615660 | chr2:141857943-141858091 | 149 nt | 0.2886 |
| hsa_LRP1B_0043800 | Intron-Intron | chr2:142616422-142616672 | chr2:141858853-141859103 | 251 nt | 0.4024 |
| hsa_LRP1B_0043900 | Intron-Intron | chr2:142619735-142620091 | chr2:141862166-141862522 | 357 nt | 0.3445 |
| hsa_LRP1B_0044000 | Intron-Intron | chr2:142619893-142620091 | chr2:141862324-141862522 | 199 nt | 0.3819 |
Showing 461 to 470 of 509 entries
Forensic Context
A study in mice demonstrated that the circLRP1B is upregulated following traumatic brain injury, and its inhibition reduces inflammation and autophagy by regulating the miR-27a-3p/Dram2 signaling pathway [Li et al. DOI:10.1016/j.neuint.2023.105643].