Basic Information

Symbol
circMACF1
RNA Class
circRNA
Alias
Microtubule Actin Crosslinking Factor 1 KIAA0754 ABP620 ACF7 Actin Cross-Linking Family Protein 7 Trabeculin-Alpha KIAA0465 KIAA1251 Lnc-PMIF MACF Postulated Migration Inhibitory Factor 620 KDa Actin Binding Protein FLJ45612 FLJ46776 Microtubule-Actin Cross-Linking Factor 1, Isoforms 1/2/3/4/5 Microtubule-Actin Cross-Linking Factor 1, Isoforms 6/7 Microtubule-Actin Cross-Linking Factor 1 Uncharacterized Protein KIAA0754 620 KDa Actin-Binding Protein Actin Cross-Linking Factor Macrophin 1 Macrophin-1 LIS9 OFC4
Location (GRCh37)
1:39547089-39951524 UCSC Genome Browser
Location (GRCh38)
Host gene
MACF1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-420K8.2_0000200 Intergenic-Exon-Intergenic chr1:39763370-39775341 chr1:39297698-39309669 456 nt 0.4781
hsa_RP11-420K8.2_0000300 Intergenic-Exon-Intergenic chr1:39763400-39775341 chr1:39297728-39309669 426 nt 0.4742
hsa_RP11-420K8.2_0000400 Intergenic-Exon-Intergenic chr1:39765978-39775961 chr1:39300306-39310289 384 nt 0.4688
hsa_RP11-420K8.2_0000500 Intergenic-Exon-Intergenic chr1:39768649-39775352 chr1:39302977-39309680 213 nt 0.4977
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Forensic Context

In mice, circMACF1 was found to be downregulated in myocardial tissue following myocardial infarction, and its experimental overexpression was shown to restore cardiomyocyte apoptosis and reduce myocardial infarct size [Tian et al. DOI:10.3390/molecules26041155].