Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0008500 Exon-Exon chr2:9048751-9098771 chr2:8908621-8958642 320 nt 0.3969
hsa_MBOAT2_0000700 Exon-Exon chr2:8996701-9098771 chr2:8856571-8958642 250 nt 0.3760
hsa_MBOAT2_0001400 Exon-Exon chr2:9000743-9008679 chr2:8860613-8868549 454 nt 0.3789
hsa_MBOAT2_0001500 Exon-Exon chr2:9000743-9098771 chr2:8860613-8958642 1262 nt 0.3994
hsa_MBOAT2_0001900 Intron-Exon-Intron chr2:9002401-9098771 chr2:8862271-8958642 1429 nt 0.4157
hsa_MBOAT2_0002700 Exon-Exon chr2:9008576-9028203 chr2:8868446-8888073 592 nt 0.4189
hsa_MBOAT2_0002800 Exon-Exon chr2:9008576-9098771 chr2:8868446-8958642 912 nt 0.4112
hsa_MBOAT2_0003300 Exon-Exon chr2:9013238-9098771 chr2:8873108-8958642 808 nt 0.4109
hsa_MBOAT2_0004100 Intron-Exon-Intron chr2:9017117-9098771 chr2:8876987-8958642 658 nt 0.4073
hsa_MBOAT2_0004400 Exon-Exon chr2:9017160-9048846 chr2:8877030-8908716 391 nt 0.4169
Showing 1 to 10 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].