Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr2_1019200 Intergenic-Intergenic chr2:9032831-9033198 chr2:8892701-8893068 368 nt 0.5054
hsa_MBOAT2_0007100 Intron-Intron chr2:9034762-9035945 chr2:8894632-8895815 1184 nt 0.4924
hsa_MBOAT2_0006900 Intron-Intron chr2:9034762-9042874 chr2:8894632-8902744 250 nt 0.3960
hsa_MBOAT2_0007000 Intron-Exon-Intron chr2:9034762-9098771 chr2:8894632-8958642 250 nt 0.3520
hsa_MBOAT2_0007200 Intron-Exon-Intron chr2:9035789-9098771 chr2:8895659-8958642 259 nt 0.4595
hsa_MBOAT2_0007300 Intron-Intron chr2:9037049-9037419 chr2:8896919-8897289 371 nt 0.4043
hsa_MBOAT2_0007400 Intron-Intron chr2:9042439-9042866 chr2:8902309-8902736 428 nt 0.5023
hsa_MBOAT2_0007500 Intron-Intron chr2:9043602-9043747 chr2:8903472-8903617 146 nt 0.3630
hsa_MBOAT2_0007600 Intron-Exon-Intron chr2:9046555-9098771 chr2:8906425-8958642 96 nt 0.4063
hsa_MBOAT2_0007700 Intron-Exon-Intron chr2:9046575-9098771 chr2:8906445-8958642 322 nt 0.4255
Showing 91 to 100 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].