Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0009500 Intron-Exon-Intron chr2:9048751-9117074 chr2:8908621-8976945 100 nt 0.3700
hsa_MBOAT2_0008800 Intron-Exon-Intron chr2:9048751-9123980 chr2:8908621-8983851 250 nt 0.3040
hsa_MBOAT2_0008900 Intron-Exon-Intron chr2:9048751-9125083 chr2:8908621-8984954 250 nt 0.3760
hsa_MBOAT2_0009000 Intron-Exon-Intron chr2:9048751-9127069 chr2:8908621-8986940 250 nt 0.3920
hsa_MBOAT2_0009800 Intron-Exon-Intron chr2:9048751-9137472 chr2:8908621-8997343 458 nt 0.4127
hsa_MBOAT2_0009900 Intron-Exon-Intron chr2:9048751-9139297 chr2:8908621-8999168 96 nt 0.4063
hsa_MBOAT2_0010000 Intron-Exon-Intron chr2:9048751-9142670 chr2:8908621-9002541 242 nt 0.4008
hsa_MBOAT2_0010100 Intron-Exon-Intron chr2:9056603-9098771 chr2:8916473-8958642 155 nt 0.3677
hsa_MBOAT2_0010200 Intron-Intron chr2:9063516-9063672 chr2:8923386-8923542 157 nt 0.4777
hsa_MBOAT2_0010300 Intron-Exon-Intron chr2:9074128-9098771 chr2:8933999-8958642 250 nt 0.3240
Showing 111 to 120 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].