Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0011300 Intron-Exon-Intron chr2:9079950-9127069 chr2:8939821-8986940 250 nt 0.3640
hsa_MBOAT2_0012000 Intron-Exon-Intron chr2:9079950-9127890 chr2:8939821-8987761 547 nt 0.4241
hsa_MBOAT2_0012100 Intron-Exon-Intron chr2:9079950-9133095 chr2:8939821-8992966 192 nt 0.3542
hsa_MBOAT2_0011400 Intron-Exon-Intron chr2:9079950-9133538 chr2:8939821-8993409 250 nt 0.3440
hsa_MBOAT2_0012200 Intron-Exon-Intron chr2:9079950-9137472 chr2:8939821-8997343 476 nt 0.3950
hsa_MBOAT2_0012300 Intron-Exon-Intron chr2:9081857-9083393 chr2:8941728-8943264 1537 nt 0.3728
hsa_MBOAT2_0012400 Intron-Exon-Intron chr2:9082932-9098771 chr2:8942803-8958642 228 nt 0.4386
hsa_MBOAT2_0012500 Intron-Exon-Intron chr2:9082932-9137472 chr2:8942803-8997343 112 nt 0.4464
hsa_MBOAT2_0013500 Intron-Exon-Intron chr2:9083316-9099957 chr2:8943187-8959828 296 nt 0.3818
hsa_MBOAT2_0013600 Intron-Exon-Intron chr2:9083316-9099994 chr2:8943187-8959865 261 nt 0.3678
Showing 131 to 140 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].