Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0015600 Intron-Exon-Intron chr2:9098626-9114564 chr2:8958497-8974435 146 nt 0.3973
hsa_MBOAT2_0015700 Intron-Exon-Intron chr2:9098626-9125083 chr2:8958497-8984954 291 nt 0.4433
hsa_MBOAT2_0015800 Intron-Exon-Intron chr2:9098626-9127890 chr2:8958497-8987761 146 nt 0.3973
hsa_MBOAT2_0015900 Intron-Exon-Intron chr2:9098626-9137472 chr2:8958497-8997343 258 nt 0.4186
hsa_MBOAT2_0016000 Intron-Intron chr2:9102445-9102731 chr2:8962316-8962602 287 nt 0.4495
hsa_chr2_1019400 Intergenic-Intergenic chr2:9106254-9106430 chr2:8966125-8966301 177 nt 0.3785
hsa_MBOAT2_0016100 Intron-Intron chr2:9114990-9115385 chr2:8974861-8975256 396 nt 0.3864
hsa_MBOAT2_0016200 Intron-Intron chr2:9117775-9118385 chr2:8977646-8978256 611 nt 0.4730
hsa_MBOAT2_0016300 Intron-Intron chr2:9117800-9118139 chr2:8977671-8978010 340 nt 0.4618
hsa_MBOAT2_0016400 Intron-Intron chr2:9121005-9121488 chr2:8980876-8981359 484 nt 0.3430
Showing 161 to 170 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].