Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr2_1019500 Intergenic-Intergenic chr2:9122186-9125129 chr2:8982057-8985000 2944 nt 0.3716
hsa_chr2_1019600 Intergenic-Intergenic chr2:9125714-9141909 chr2:8985585-9001780 250 nt 0.2800
hsa_MBOAT2_0016500 Intron-Intron chr2:9126182-9137472 chr2:8986053-8997343 272 nt 0.4191
hsa_MBOAT2_0016700 Intron-Intron chr2:9126802-9127890 chr2:8986673-8987761 109 nt 0.4954
hsa_MBOAT2_0016600 Intron-Intron chr2:9126802-9137472 chr2:8986673-8997343 250 nt 0.3920
hsa_MBOAT2_0016800 Intron-Intron chr2:9129090-9129388 chr2:8988961-8989259 299 nt 0.3579
hsa_MBOAT2_0016900 Intron-Intron chr2:9130769-9131114 chr2:8990640-8990985 346 nt 0.3324
hsa_MBOAT2_0017000 Intron-Intron chr2:9130934-9131114 chr2:8990805-8990985 181 nt 0.3646
hsa_chr2_1019700 Intergenic-Intergenic chr2:9134149-9134319 chr2:8994020-8994190 171 nt 0.4971
hsa_snoU13_0007800 Intergenic-Exon-Intergenic chr2:9098743-9143714 chr2:8958614-9003585 75 nt 0.6000
Showing 171 to 180 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].