Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0009700 Intron-Exon-Intron chr2:9048751-9127890 chr2:8908621-8987761 250 nt 0.3600
hsa_MBOAT2_0010900 Intron-Exon-Intron chr2:9079950-9083393 chr2:8939821-8943264 250 nt 0.2800
hsa_MBOAT2_0011000 Intron-Exon-Intron chr2:9079950-9098771 chr2:8939821-8958642 250 nt 0.2880
hsa_MBOAT2_0011100 Intron-Exon-Intron chr2:9079950-9099994 chr2:8939821-8959865 250 nt 0.2520
hsa_MBOAT2_0011700 Intron-Exon-Intron chr2:9079950-9114564 chr2:8939821-8974435 250 nt 0.3520
hsa_MBOAT2_0012600 Exon-Exon chr2:9083316-9083393 chr2:8943187-8943264 78 nt 0.3846
hsa_MBOAT2_0012700 Exon-Exon chr2:9083316-9098771 chr2:8943187-8958642 224 nt 0.3929
hsa_MBOAT2_0012800 Intron-Exon-Intron chr2:9083316-9102747 chr2:8943187-8962618 250 nt 0.3480
hsa_MBOAT2_0013900 Exon-Exon chr2:9083316-9114564 chr2:8943187-8974435 250 nt 0.3720
hsa_MBOAT2_0014100 Intron-Exon-Intron chr2:9083316-9122273 chr2:8943187-8982144 250 nt 0.3520
Showing 21 to 30 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].