Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0014700 Intron-Exon-Intron chr2:9083316-9127890 chr2:8943187-8987761 250 nt 0.3520
hsa_MBOAT2_0015000 Intron-Exon-Intron chr2:9083316-9137472 chr2:8943187-8997343 250 nt 0.3360
hsa_MBOAT2_0012900 Exon-Exon chr2:9083316-9143876 chr2:8943187-9003747 432 nt 0.5833
hsa_MBOAT2_0015300 Exon-Exon chr2:9098626-9098771 chr2:8958497-8958642 146 nt 0.3973
hsa_MBOAT2_0000100 Intergenic-Exon chr2:8957748-9098771 chr2:8817618-8958642 250 nt 0.3360
hsa_MBOAT2_0000200 Intergenic-Exon chr2:8967116-9098771 chr2:8826986-8958642 146 nt 0.3973
hsa_MBOAT2_0000300 Intergenic-Exon chr2:8988275-9098771 chr2:8848145-8958642 250 nt 0.3960
hsa_chr2_1018900 Intergenic-Intergenic chr2:8993454-8993909 chr2:8853324-8853779 456 nt 0.3487
hsa_chr2_1019000 Intergenic-Intergenic chr2:8995457-8995632 chr2:8855327-8855502 176 nt 0.4261
hsa_MBOAT2_0000500 Exon-Exon chr2:8995799-9008679 chr2:8855669-8868549 296 nt 0.3378
Showing 31 to 40 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].