Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
2:8817618-9003747
UCSC Genome Browser Search in Marker Scope
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0000600 Exon-Exon chr2:8995799-9098771 chr2:8855669-8958642 64 nt 0.3438
hsa_MBOAT2_0000800 Exon-Exon chr2:8997446-8998493 chr2:8857316-8858363 1048 nt 0.3721
hsa_MBOAT2_0000900 Exon-Exon chr2:8998176-8998319 chr2:8858046-8858189 144 nt 0.3056
hsa_MBOAT2_0001000 Exon-Exon chr2:8998291-8998493 chr2:8858161-8858363 203 nt 0.3300
hsa_chr2_1019100 Intergenic-Intergenic chr2:8998411-9000814 chr2:8858281-8860684 696 nt 0.4009
hsa_MBOAT2_0001100 Exon-Intron chr2:8998606-9035945 chr2:8858476-8895815 250 nt 0.3840
hsa_MBOAT2_0001200 Exon-Exon chr2:8998606-9048846 chr2:8858476-8908716 1467 nt 0.3988
hsa_MBOAT2_0001300 Exon-Exon chr2:8998606-9098771 chr2:8858476-8958642 224 nt 0.3929
hsa_MBOAT2_0001600 Exon-Exon chr2:9000743-9004364 chr2:8860613-8864234 402 nt 0.3582
hsa_MBOAT2_0001700 Exon-Exon chr2:9000743-9008642 chr2:8860613-8868512 284 nt 0.3380
Showing 41 to 50 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].