Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0001800 Exon-Exon chr2:9000743-9008655 chr2:8860613-8868525 152 nt 0.3092
hsa_MBOAT2_0002000 Exon-Exon chr2:9002720-9017343 chr2:8862590-8877213 679 nt 0.4168
hsa_MBOAT2_0002100 Intron-Exon-Intron chr2:9002720-9114564 chr2:8862590-8974435 265 nt 0.4113
hsa_MBOAT2_0002200 Intron-Exon-Intron chr2:9004300-9013175 chr2:8864170-8873045 250 nt 0.2760
hsa_MBOAT2_0002400 Exon-Exon chr2:9004300-9022695 chr2:8864170-8882565 55 nt 0.4545
hsa_MBOAT2_0002500 Exon-Exon chr2:9004300-9028203 chr2:8864170-8888073 176 nt 0.3920
hsa_MBOAT2_0002300 Exon-Exon chr2:9004300-9048846 chr2:8864170-8908716 753 nt 0.4104
hsa_MBOAT2_0002600 Exon-Exon chr2:9004300-9098771 chr2:8864170-8958642 175 nt 0.3886
hsa_MBOAT2_0002900 Exon-Exon chr2:9008576-9022695 chr2:8868446-8882565 159 nt 0.4277
hsa_MBOAT2_0003000 Exon-Exon chr2:9008576-9048846 chr2:8868446-8908716 104 nt 0.4135
Showing 51 to 60 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].