Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0003100 Exon-Exon chr2:9008576-9083393 chr2:8868446-8943264 200 nt 0.4100
hsa_MBOAT2_0003200 Intron-Exon-Intron chr2:9013084-9098771 chr2:8872954-8958642 962 nt 0.4075
hsa_MBOAT2_0003600 Exon-Exon chr2:9013238-9013430 chr2:8873108-8873300 193 nt 0.4197
hsa_MBOAT2_0003700 Exon-Exon chr2:9013238-9022695 chr2:8873108-8882565 432 nt 0.4236
hsa_MBOAT2_0004000 Exon-Exon chr2:9013238-9028203 chr2:8873108-8888073 304 nt 0.4211
hsa_MBOAT2_0003400 Intron-Exon-Intron chr2:9013238-9035945 chr2:8873108-8895815 250 nt 0.3600
hsa_MBOAT2_0003800 Exon-Exon chr2:9013238-9048846 chr2:8873108-8908716 584 nt 0.4178
hsa_MBOAT2_0003500 Intron-Exon-Intron chr2:9013238-9076912 chr2:8873108-8936783 250 nt 0.4000
hsa_MBOAT2_0003900 Exon-Exon chr2:9013238-9083393 chr2:8873108-8943264 662 nt 0.4139
hsa_MBOAT2_0004200 Intron-Exon-Intron chr2:9017117-9048846 chr2:8876987-8908716 282 nt 0.4220
Showing 61 to 70 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].