Basic Information

Symbol
circMBOAT2
RNA Class
circRNA
Alias
Membrane Bound Glycerophospholipid O-Acyltransferase 2 Lysophospholipid Acyltransferase 2 LPLAT13 OACT2 Membrane-Bound O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphoethanolamine MBOAT2 O-Acyltransferase O-Acyltransferase (Membrane Bound) Domain Containing 2 Membrane-Bound Glycerophospholipid O-Acyltransferase 2 Membrane Bound O-Acyltransferase Domain Containing 2 1-Acylglycerophosphocholine O-Acyltransferase MBOAT2 1-Acylglycerophosphate O-Acyltransferase MBOAT2 Lysophosphatidylethanolamine Acyltransferase Lysophosphatidylcholine Acyltransferase 4 Lysophosphatidylcholine Acyltransferase Lysophosphatidic Acid Acyltransferase Lysophospholipid Acyltransferase 13 Lyso-PC Acyltransferase 4 Lyso-PA Acyltransferase Lyso-PC Acyltransferase Lyso-PE Acyltransferase FLJ14415 FLJ90298 LPLAT 2 LPCAT4 LPAAT LPCAT LPEAT 1-Acylglycerophosphoethanolamine O-Acyltransferase O-Acyltransferase Domain-Containing Protein 2 1-Acylglycerophosphate O-Acyltransferase EC 2.3.1.51 EC 2.3.1.23 EC 2.3.1.N7 EC 2.3.1.-
Location (GRCh37)
2:8957748-9143876 UCSC Genome Browser
Location (GRCh38)
Host gene
MBOAT2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MBOAT2_0004300 Intron-Exon-Intron chr2:9017155-9098771 chr2:8877025-8958642 335 nt 0.4090
hsa_MBOAT2_0004600 Exon-Exon chr2:9017160-9028203 chr2:8877030-8888073 62 nt 0.3871
hsa_MBOAT2_0004700 Intron-Exon-Intron chr2:9017160-9075266 chr2:8877030-8935137 184 nt 0.4185
hsa_MBOAT2_0004800 Exon-Exon chr2:9017160-9083393 chr2:8877030-8943264 78 nt 0.3846
hsa_MBOAT2_0004900 Intron-Exon-Intron chr2:9017160-9114564 chr2:8877030-8974435 184 nt 0.4185
hsa_MBOAT2_0005000 Intron-Exon-Intron chr2:9017160-9120751 chr2:8877030-8980622 184 nt 0.4185
hsa_MBOAT2_0005100 Intron-Exon-Intron chr2:9017160-9127890 chr2:8877030-8987761 109 nt 0.4954
hsa_MBOAT2_0005600 Exon-Exon chr2:9022641-9048846 chr2:8882511-8908716 207 nt 0.4155
hsa_MBOAT2_0005700 Intron-Exon-Intron chr2:9022641-9080063 chr2:8882511-8939934 225 nt 0.3778
hsa_MBOAT2_0005800 Exon-Exon chr2:9022641-9114564 chr2:8882511-8974435 56 nt 0.3929
Showing 71 to 80 of 180 entries
Forensic Context

A study in humans demonstrated that the circMBOAT2 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing an area under the curve (AUC) of 0.756 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155]. A study in human peripheral bloodstains demonstrated that the circMBOAT2 exhibited a unique, linear degradation profile over a 120-day storage interval, with its relative expression levels showing a significant negative correlation with bloodstain age under outdoor conditions (r=0.82) [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. This circRNA biomarker, along with others, showed continuous degradation useful for time since deposition estimation, and its application for bloodstain dating has been noted in broader reviews of molecular forensic methods [Mróz et al. DOI:10.1016/j.jflm.2025.102946].