Basic Information

Symbol
circMMP10
RNA Class
circRNA
Alias
Matrix Metallopeptidase 10 STMY2 Matrix Metalloproteinase 10 (Stromelysin 2) Matrix Metalloproteinase-10 Stromelysin-2 MMP-10 SL-2 Matrix Metalloprotease 10 Stromelysin 2 EC 3.4.24.22 Transin 2 Transin-2 EC 3.4.24
Location (GRCh37)
11:102641233-102650476 UCSC Genome Browser
Location (GRCh38)
11:102770502-102779745
UCSC Genome Browser Search in Marker Scope
Host gene
MMP10
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_MMP10_0000100 Intergenic-Exon chr11:102641233-102650092 chr11:102770502-102779361 1375 nt 0.4247
hsa_MMP10_0000200 Intergenic-Exon chr11:102641233-102650476 chr11:102770502-102779745 1617 nt 0.4304
hsa_MMP10_0000400 Exon-Exon chr11:102643578-102650476 chr11:102772847-102779745 1121 nt 0.4567
hsa_MMP10_0000300 Exon-Exon chr11:102642743-102650476 chr11:102772012-102779745 1225 nt 0.4547
Forensic Context

A review of circular RNAs in human diseases consolidates findings that the circMMP10 is not specifically discussed in the provided literature, which instead details numerous other circRNAs with altered expression in various cancers, neurological disorders, and cardiovascular conditions [Lee et al. DOI:10.1016/j.biopha.2018.12.052]. The literature extensively documents the role of circRNAs as miRNA sponges, regulators of transcription and translation, and their potential as clinical biomarkers in biofluids like blood and saliva [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans demonstrated that the circular RNA (circRNA) form of MMP10, a menstrual blood-specific biomarker, was detectable in all menstrual blood samples and exhibited high specificity [Liu et al. DOI:10.1016/J.Fsigen.2020.102312].