Basic Information
Symbol
circMORC3
RNA Class
circRNA
Alias
MORC Family CW-Type Zinc Finger 3
NXP2
KIAA0136
ZCWCC3
ZCW5
Zinc Finger CW-Type Coiled-Coil Domain Protein 3
Zinc Finger, CW Type With Coiled-Coil Domain 3
MORC Family CW-Type Zinc Finger Protein 3
Nuclear Matrix Protein 2
Zinc Finger, CW-Type With Coiled-Coil Domain 3
Nuclear Matrix Protein NXP2
Location (GRCh37)
21:37711077-37717005
UCSC Genome Browser
Location (GRCh38)
21:36338779-36344707
Host gene
MORC3
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_MORC3_0006600 | Exon-Exon | chr21:37711077-37717005 | chr21:36338779-36344707 | 420 nt | 0.4048 |
Forensic Context
A study in humans demonstrated that the circMORC3 is expressed in spermatozoa and specifically interacts with five miRNAs involved in cell cycle control, suggesting a role as a paternal-derived miRNA sponge within fertilized oocytes [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans identified hsa_circ_0001189 as one of 736 differentially expressed circular RNAs in peripheral blood from ischemic stroke patients, where it was up-regulated with a log2 fold change of 2.129201 and its host gene is MORC3 [Wei et al. DOI: 10.1186/s12883-021-02397-0].