Basic Information
Symbol
circMROH7-TTC4
RNA Class
circRNA
Alias
MROH7-TTC4 Readthrough (NMD Candidate)
Maestro Heat-Like Repeat-Containing Protein Family Member 7
HEAT Repeat-Containing Protein 8
HEATR8-TTC4 Readthrough
HEATR8-TTC4
C1orf175
HEATR8
MROH7
Location (GRCh37)
1:55197159-55197373
UCSC Genome Browser
Location (GRCh38)
1:54731486-54731700
Host gene
MROH7-TTC4
Host category
lncRNA
Forensic tag(s)
Drug abuse diagnoses
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_MROH7-TTC4_0002000 | Exon-Exon | chr1:55197159-55197373 | chr1:54731486-54731700 | 215 nt | 0.5442 |
Forensic Context
A study in mice demonstrated that cocaine self-administration induces differential expression of 90 striatal circular RNAs, with 18 up-regulated and 72 down-regulated [Bu et al. DOI:10.1038/S41398-019-0527-1]. A study in humans demonstrated that the circMROH7-TTC4 was exclusively detected in atrial tissues from patients with permanent atrial fibrillation, indicating its potential as a disease-specific biomarker [Tian et al. DOI:10.3390/molecules26041155].