Basic Information
Symbol
circMTO1
RNA Class
circRNA
Alias
Mitochondrial TRNA Translation Optimization 1
5-Taurinomethyluridine-[TRNA] Synthase Subunit MTO1, Mitochondrial
Protein MTO1 Homolog, Mitochondrial
Mitochondrial Translation Optimization 1 Homolog (S. Cerevisiae)
Mitochondrial Translation Optimization 1 Homolog
Homolog Of Yeast Mto1
Mitochondrial MTO1-3
EC 1.1.1.40
EC 6.3.5
COXPD10
CGI-02
Location (GRCh37)
6:74172360-74213411
UCSC Genome Browser
Location (GRCh38)
6:73462637-73503688
Host gene
MTO1
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RP11-505P4.6_0000300 | Intergenic-Intron | chr6:74201535-74202221 | chr6:73491812-73492498 | 687 nt | 0.4163 |
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Forensic Context
A review consolidating existing research indicates that the circMTO1 functions as a tumor suppressor in hepatocellular carcinoma [Lee et al. DOI:10.1016/j.biopha.2018.12.052] and sponges miR-630 to reverse temozolomide chemoresistance in glioblastoma [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].