Basic Information
Symbol
circNEIL3
RNA Class
circRNA
Alias
Nei Like DNA Glycosylase 3
HFPG2
HNEI3
ZGRF3
FPG2
Zinc Finger, GRF-Type Containing 3
DNA Glycosylase/AP Lyase Neil3
Endonuclease VIII-Like 3
Endonuclease 8-Like 3
DNA Glycosylase FPG2
Nei-Like Protein 3
FLJ10858
Nei Endonuclease VIII-Like 3 (E. Coli)
Nei Endonuclease VIII-Like 3
DNA Glycosylase HFPG2
EC 4.2.99.18
EC 3.2.2.-
FGP2
NEI3
Location (GRCh37)
4:178274462-178281831
UCSC Genome Browser
Location (GRCh38)
4:177353308-177360677
Host gene
NEIL3
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_NEIL3_0003400 | Exon-Exon | chr4:178274462-178274882 | chr4:177353308-177353728 | 421 nt | 0.3682 |
| hsa_NEIL3_0003500 | Exon-Exon | chr4:178274462-178281831 | chr4:177353308-177360677 | 596 nt | 0.3977 |
Forensic Context
A study in humans identified 736 differentially expressed circRNAs in peripheral blood from ischemic stroke patients, with the circNEIL3 being significantly up-regulated and validated by qRT-PCR [Wei et al. DOI:10.1186/s12883-021-02397-0].