Basic Information
Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X
NF1A
CCAAT-Box-Binding Transcription Factor
Nuclear Factor 1 X-Type
TGGCA-Binding Protein
Nuclear Factor 1/X
NF-I/X
NF1-X
CTF
Nuclear Factor I/X (CCAAT-Binding Transcription Factor)
CCAAT-Binding Transcription Factor
Nuclear Factor I/X
MRSHSS
SOTOS2
MALNS
NFI-X
Location (GRCh37)
19:13120851-13207654
UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_NFIX_0000300 | Exon-Exon | chr19:13135835-13136366 | chr19:13025021-13025552 | 532 nt | 0.5959 |
| hsa_NFIX_0002500 | Exon-Exon | chr19:13183861-13184840 | chr19:13073047-13074026 | 259 nt | 0.5560 |
| hsa_NFIX_0002600 | Exon-Exon | chr19:13183861-13186485 | chr19:13073047-13075671 | 396 nt | 0.5783 |
| hsa_NFIX_0002800 | Exon-Exon | chr19:13183861-13192669 | chr19:13073047-13081855 | 695 nt | 0.6014 |
| hsa_NFIX_0003300 | Exon-Exon | chr19:13186349-13189549 | chr19:13075535-13078735 | 260 nt | 0.6192 |
| hsa_chr19_0045600 | Intergenic-Intergenic | chr19:13192537-13198938 | chr19:13081723-13088124 | 250 nt | 0.4840 |
| hsa_AC007787.2_0000100 | Intergenic-Exon-Intergenic | chr19:13135904-13206022 | chr19:13025090-13095208 | 1972 nt | 0.5969 |
| hsa_NFIX_0000100 | Intron-Intron | chr19:13120851-13122263 | chr19:13010037-13011449 | 1413 nt | 0.6277 |
| hsa_NFIX_0000200 | Intron-Intron | chr19:13134472-13134848 | chr19:13023658-13024034 | 377 nt | 0.5146 |
| hsa_NFIX_0000600 | Exon-Intron | chr19:13135835-13136370 | chr19:13025021-13025556 | 536 nt | 0.5951 |
Showing 1 to 10 of 59 entries
Forensic Context
A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].