Basic Information
Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X
NF1A
CCAAT-Box-Binding Transcription Factor
Nuclear Factor 1 X-Type
TGGCA-Binding Protein
Nuclear Factor 1/X
NF-I/X
NF1-X
CTF
Nuclear Factor I/X (CCAAT-Binding Transcription Factor)
CCAAT-Binding Transcription Factor
Nuclear Factor I/X
MRSHSS
SOTOS2
MALNS
NFI-X
Location (GRCh37)
19:13120851-13207654
UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_NFIX_0000400 | Exon-Intron | chr19:13135835-13178248 | chr19:13025021-13067434 | 250 nt | 0.4520 |
| hsa_NFIX_0000700 | Exon-Exon | chr19:13135835-13184310 | chr19:13025021-13073496 | 670 nt | 0.5761 |
| hsa_NFIX_0001000 | Exon-Exon | chr19:13135835-13184796 | chr19:13025021-13073982 | 63 nt | 0.4921 |
| hsa_NFIX_0000800 | Exon-Exon | chr19:13135835-13186485 | chr19:13025021-13075671 | 928 nt | 0.5884 |
| hsa_NFIX_0000900 | Exon-Exon | chr19:13135835-13189549 | chr19:13025021-13078735 | 1051 nt | 0.5918 |
| hsa_NFIX_0001100 | Exon-Exon | chr19:13135835-13192669 | chr19:13025021-13081855 | 348 nt | 0.6236 |
| hsa_NFIX_0001200 | Exon-Exon | chr19:13135835-13198950 | chr19:13025021-13088136 | 198 nt | 0.6010 |
| hsa_NFIX_0000500 | Exon-Exon | chr19:13135835-13206543 | chr19:13025021-13095729 | 2414 nt | 0.6143 |
| hsa_chr19_0044700 | Intergenic-Intergenic | chr19:13135894-13136230 | chr19:13025080-13025416 | 337 nt | 0.6202 |
| hsa_NFIX_0001400 | Exon-Exon | chr19:13135910-13136366 | chr19:13025096-13025552 | 457 nt | 0.5974 |
Showing 11 to 20 of 59 entries
Forensic Context
A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].