Basic Information

Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X NF1A CCAAT-Box-Binding Transcription Factor Nuclear Factor 1 X-Type TGGCA-Binding Protein Nuclear Factor 1/X NF-I/X NF1-X CTF Nuclear Factor I/X (CCAAT-Binding Transcription Factor) CCAAT-Binding Transcription Factor Nuclear Factor I/X MRSHSS SOTOS2 MALNS NFI-X
Location (GRCh37)
19:13120851-13207654 UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
UCSC Genome Browser Search in Marker Scope
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_NFIX_0001500 Exon-Exon chr19:13136018-13136182 chr19:13025204-13025368 165 nt 0.6606
hsa_NFIX_0001600 Exon-Exon chr19:13136273-13184796 chr19:13025459-13073982 246 nt 0.5325
hsa_NFIX_0001700 Intron-Exon-Intron chr19:13155182-13184840 chr19:13044368-13074026 250 nt 0.4680
hsa_NFIX_0001800 Intron-Exon-Intron chr19:13155182-13186485 chr19:13044368-13075671 250 nt 0.4640
hsa_NFIX_0001900 Intron-Intron chr19:13158107-13158822 chr19:13047293-13048008 716 nt 0.5112
hsa_chr19_0044800 Intergenic-Intergenic chr19:13164004-13165246 chr19:13053190-13054432 1243 nt 0.5736
hsa_NFIX_0002000 Intron-Intron chr19:13175706-13177005 chr19:13064892-13066191 1300 nt 0.5531
hsa_NFIX_0002100 Intron-Exon-Intron chr19:13175794-13192669 chr19:13064980-13081855 250 nt 0.4680
hsa_NFIX_0002200 Intron-Exon-Intron chr19:13178159-13186485 chr19:13067345-13075671 250 nt 0.4760
hsa_NFIX_0002300 Intron-Exon-Intron chr19:13178159-13189549 chr19:13067345-13078735 123 nt 0.6179
Showing 21 to 30 of 59 entries
Forensic Context

A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].