Basic Information

Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X NF1A CCAAT-Box-Binding Transcription Factor Nuclear Factor 1 X-Type TGGCA-Binding Protein Nuclear Factor 1/X NF-I/X NF1-X CTF Nuclear Factor I/X (CCAAT-Binding Transcription Factor) CCAAT-Binding Transcription Factor Nuclear Factor I/X MRSHSS SOTOS2 MALNS NFI-X
Location (GRCh37)
19:13120851-13207654 UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
UCSC Genome Browser Search in Marker Scope
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_NFIX_0002400 Intron-Exon-Intron chr19:13178159-13201204 chr19:13067345-13090390 121 nt 0.6198
hsa_NFIX_0002700 Exon-Exon chr19:13183861-13189549 chr19:13073047-13078735 519 nt 0.5877
hsa_NFIX_0002900 Exon-Exon chr19:13183861-13201204 chr19:13073047-13090390 184 nt 0.5761
hsa_NFIX_0003000 Exon-Exon chr19:13183890-13184796 chr19:13073076-13073982 186 nt 0.5430
hsa_NFIX_0003100 Exon-Exon chr19:13184236-13184840 chr19:13073422-13074026 127 nt 0.6220
hsa_NFIX_0003200 Exon-Exon chr19:13184720-13189549 chr19:13073906-13078735 129 nt 0.6202
hsa_chr19_0044900 Intergenic-Intergenic chr19:13184823-13186564 chr19:13074009-13075750 234 nt 0.6154
hsa_chr19_0045000 Intergenic-Intergenic chr19:13184823-13188163 chr19:13074009-13077349 1833 nt 0.5996
hsa_chr19_0045100 Intergenic-Intergenic chr19:13184823-13189473 chr19:13074009-13078659 47 nt 0.5532
hsa_chr19_0045200 Intergenic-Intergenic chr19:13184823-13201131 chr19:13074009-13090317 621 nt 0.6312
Showing 31 to 40 of 59 entries
Forensic Context

A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].