Basic Information
Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X
NF1A
CCAAT-Box-Binding Transcription Factor
Nuclear Factor 1 X-Type
TGGCA-Binding Protein
Nuclear Factor 1/X
NF-I/X
NF1-X
CTF
Nuclear Factor I/X (CCAAT-Binding Transcription Factor)
CCAAT-Binding Transcription Factor
Nuclear Factor I/X
MRSHSS
SOTOS2
MALNS
NFI-X
Location (GRCh37)
19:13120851-13207654
UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr19_0045300 | Intergenic-Intergenic | chr19:13184954-13185105 | chr19:13074140-13074291 | 152 nt | 0.5526 |
| hsa_NFIX_0003400 | Exon-Exon | chr19:13186349-13201204 | chr19:13075535-13090390 | 229 nt | 0.6114 |
| hsa_chr19_0045400 | Intergenic-Intergenic | chr19:13186380-13201136 | chr19:13075566-13090322 | 130 nt | 0.6231 |
| hsa_chr19_0045500 | Intergenic-Intergenic | chr19:13186944-13187202 | chr19:13076130-13076388 | 259 nt | 0.5328 |
| hsa_NFIX_0003500 | Exon-Exon | chr19:13189427-13192669 | chr19:13078613-13081855 | 299 nt | 0.6321 |
| hsa_NFIX_0003600 | Exon-Exon | chr19:13189427-13201204 | chr19:13078613-13090390 | 391 nt | 0.6240 |
| hsa_NFIX_0003700 | Exon-Exon | chr19:13189427-13206543 | chr19:13078613-13095729 | 123 nt | 0.6179 |
| hsa_NFIX_0003800 | Exon-Exon | chr19:13192494-13201204 | chr19:13081680-13090390 | 268 nt | 0.6269 |
| hsa_NFIX_0003900 | Exon-Exon | chr19:13192550-13201204 | chr19:13081736-13090390 | 212 nt | 0.6132 |
| hsa_NFIX_0004000 | Intron-Intron | chr19:13198004-13198210 | chr19:13087190-13087396 | 207 nt | 0.5507 |
Showing 41 to 50 of 59 entries
Forensic Context
A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].