Basic Information
Symbol
circNFIX
RNA Class
circRNA
Alias
Nuclear Factor I X
NF1A
CCAAT-Box-Binding Transcription Factor
Nuclear Factor 1 X-Type
TGGCA-Binding Protein
Nuclear Factor 1/X
NF-I/X
NF1-X
CTF
Nuclear Factor I/X (CCAAT-Binding Transcription Factor)
CCAAT-Binding Transcription Factor
Nuclear Factor I/X
MRSHSS
SOTOS2
MALNS
NFI-X
Location (GRCh37)
19:13120851-13207654
UCSC Genome Browser
Location (GRCh38)
19:13010037-13096840
Host gene
NFIX
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr19_0045700 | Intergenic-Intergenic | chr19:13198873-13200083 | chr19:13088059-13089269 | 1211 nt | 0.5789 |
| hsa_NFIX_0004100 | Exon-Exon | chr19:13201113-13206543 | chr19:13090299-13095729 | 92 nt | 0.5978 |
| hsa_NFIX_0004200 | Intron-Intron | chr19:13202808-13203372 | chr19:13091994-13092558 | 565 nt | 0.5929 |
| hsa_NFIX_0004300 | Exon-Exon | chr19:13205449-13206543 | chr19:13094635-13095729 | 1095 nt | 0.6329 |
| hsa_NFIX_0004400 | Exon-Exon | chr19:13205770-13206386 | chr19:13094956-13095572 | 617 nt | 0.6580 |
| hsa_NFIX_0004500 | Exon-Exon | chr19:13206358-13206591 | chr19:13095544-13095777 | 234 nt | 0.7094 |
| hsa_NFIX_0004600 | Exon-Exon | chr19:13206387-13207654 | chr19:13095573-13096840 | 1268 nt | 0.6238 |
| hsa_NFIX_0004700 | Exon-Exon | chr19:13206544-13207473 | chr19:13095730-13096659 | 930 nt | 0.5914 |
| hsa_NFIX_0004800 | Exon-Exon | chr19:13206917-13207064 | chr19:13096103-13096250 | 148 nt | 0.5270 |
Showing 51 to 59 of 59 entries
Forensic Context
A study in mice demonstrated that the circNFIX is highly expressed in adult heart tissue [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in rats demonstrated that the circNFIX exhibited dynamic expression changes in ischemic heart disease models, showing early elevation followed by downregulation in ventricular arrhythmia, coronary artery ligation, and isoproterenol-induced acute myocardial infarction models, as well as in H9c2 cells under ischemia-hypoxia [Tian et al. DOI:10.1038/s41598-021-84056-5].