Basic Information

Symbol
circNSUN2
RNA Class
circRNA
Alias
NOP2/Sun RNA Methyltransferase 2 TRM4 Misu SAKI RNA Cytosine C(5)-Methyltransferase NSUN2 Myc-Induced SUN-Domain-Containing Protein Myc-Induced SUN Domain-Containing Protein NOL1/NOP2/Sun Domain Family, Member 2 MRNA Cytosine C(5)-Methyltransferase TRNA Cytosine C(5)-Methyltransferase Substrate Of AIM1/Aurora Kinase B NOP2/Sun Domain Family, Member 2 TRNA Methyltransferase 4 Homolog FLJ20303 MRT5 Mental Retardation, Non-Syndromic, Autosomal Recessive, 5 TRNA Methyltransferase 4 Homolog (S. Cerevisiae) NOP2/Sun RNA Methyltransferase Family Member 2 TRNA (Cytosine(34)-C(5))-Methyltransferase TRNA (Cytosine-5-)-Methyltransferase NSUN2 NOL1/NOP2/Sun Domain Family Member 2 5-Methycytoisine Methyltransferase EC 2.1.1.203 EC 2.1.1.29 EC 2.1.1.- EC 2.1.1 HTrm4
Location (GRCh37)
5:6599352-6632869 UCSC Genome Browser
Location (GRCh38)
Host gene
NSUN2
Host category
mRNA
Forensic tag(s)
Other applications
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_NSUN2_0005100 Exon-Exon chr5:6620219-6623398 chr5:6620106-6623285 350 nt 0.4886
hsa_NSUN2_0005200 Exon-Exon chr5:6620219-6632090 chr5:6620106-6631977 561 nt 0.4563
hsa_NSUN2_0006100 Intron-Exon-Intron chr5:6623327-6623504 chr5:6623214-6623391 178 nt 0.3820
hsa_NSUN2_0006200 Intron-Intron chr5:6624069-6624604 chr5:6623956-6624491 536 nt 0.4590
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Forensic Context

A study in mice demonstrated that the circNSUN2 is a biomarker for liver metastasis of colorectal cancer, where its m6A modification facilitates export and it forms a complex with IGF2BP2 protein and HMGA2 RNA to enhance HMGA2 mRNA stability [Misir et al. DOI:10.1038/s41418-022-00948-7].