Basic Information

Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase OGDC-E1 OGDH2 KGD1 E1k Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide) 2-Oxoglutarate Dehydrogenase Complex Component E1 2-Oxoglutarate Dehydrogenase, Mitochondrial Alpha-KGDH-E1 EC 1.2.4.2 OGDH-E1 HsOGDH E1o Oxoglutarate Dehydrogenase (Succinyl-Transferring) Alpha-Ketoglutarate Dehydrogenase Testicular Tissue Protein Li 131 Oxoglutarate Decarboxylase AKGDH OGDHD OGDC
Location (GRCh37)
7:44654708-44748474 UCSC Genome Browser
Location (GRCh38)
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_OGDH_0000600 Exon-Exon chr7:44663916-44687133 chr7:44624317-44647534 532 nt 0.5019
hsa_OGDH_0000700 Exon-Exon chr7:44663916-44687358 chr7:44624317-44647759 544 nt 0.5239
hsa_OGDH_0001800 Exon-Exon chr7:44663916-44721447 chr7:44624317-44681848 1362 nt 0.5396
hsa_OGDH_0001900 Exon-Exon chr7:44663916-44741214 chr7:44624317-44701615 2659 nt 0.5517
hsa_OGDH_0002300 Intron-Exon-Intron chr7:44684895-44685117 chr7:44645296-44645518 223 nt 0.5830
hsa_OGDH_0002400 Exon-Exon chr7:44684926-44687133 chr7:44645327-44647534 283 nt 0.5477
hsa_OGDH_0002500 Exon-Exon chr7:44684926-44687358 chr7:44645327-44647759 295 nt 0.5864
hsa_OGDH_0002600 Intron-Exon-Intron chr7:44684926-44688811 chr7:44645327-44649212 1748 nt 0.5023
hsa_OGDH_0002800 Exon-Exon chr7:44684926-44695961 chr7:44645327-44656362 340 nt 0.5647
hsa_OGDH_0002700 Exon-Exon chr7:44684926-44706450 chr7:44645327-44666851 411 nt 0.5839
Showing 1 to 10 of 120 entries
Forensic Context

A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.