Basic Information

Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase OGDC-E1 OGDH2 KGD1 E1k Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide) 2-Oxoglutarate Dehydrogenase Complex Component E1 2-Oxoglutarate Dehydrogenase, Mitochondrial Alpha-KGDH-E1 EC 1.2.4.2 OGDH-E1 HsOGDH E1o Oxoglutarate Dehydrogenase (Succinyl-Transferring) Alpha-Ketoglutarate Dehydrogenase Testicular Tissue Protein Li 131 Oxoglutarate Decarboxylase AKGDH OGDHD OGDC
Location (GRCh37)
7:44654708-44748474 UCSC Genome Browser
Location (GRCh38)
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_OGDH_0007200 Exon-Exon chr7:44721319-44741214 chr7:44681720-44701615 202 nt 0.5495
hsa_chr7_0419400 Intergenic-Intergenic chr7:44721411-44737034 chr7:44681812-44697435 37 nt 0.5676
hsa_OGDH_0007300 Intron-Intron chr7:44723839-44724041 chr7:44684240-44684442 203 nt 0.3498
hsa_chr7_0419500 Intergenic-Intergenic chr7:44728262-44728744 chr7:44688663-44689145 483 nt 0.4990
hsa_OGDH_0007800 Exon-Exon chr7:44733424-44747594 chr7:44693825-44707995 1729 nt 0.5720
hsa_OGDH_0007900 Exon-Exon chr7:44733570-44734168 chr7:44693971-44694569 180 nt 0.5667
hsa_OGDH_0008000 Exon-Exon chr7:44733586-44734168 chr7:44693987-44694569 164 nt 0.5671
hsa_OGDH_0008200 Exon-Exon chr7:44734023-44739868 chr7:44694424-44700269 103 nt 0.4466
hsa_OGDH_0008300 Exon-Exon chr7:44736028-44737381 chr7:44696429-44697782 584 nt 0.5839
hsa_chr7_0419600 Intergenic-Intergenic chr7:44736086-44736560 chr7:44696487-44696961 119 nt 0.4958
Showing 91 to 100 of 120 entries
Forensic Context

A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.