Basic Information
Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase
OGDC-E1
OGDH2
KGD1
E1k
Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase
Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide)
2-Oxoglutarate Dehydrogenase Complex Component E1
2-Oxoglutarate Dehydrogenase, Mitochondrial
Alpha-KGDH-E1
EC 1.2.4.2
OGDH-E1
HsOGDH
E1o
Oxoglutarate Dehydrogenase (Succinyl-Transferring)
Alpha-Ketoglutarate Dehydrogenase
Testicular Tissue Protein Li 131
Oxoglutarate Decarboxylase
AKGDH
OGDHD
OGDC
Location (GRCh37)
7:44654708-44748474
UCSC Genome Browser
Location (GRCh38)
7:44615109-44708875
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_OGDH_0003100 | Exon-Exon | chr7:44684926-44721447 | chr7:44645327-44681848 | 1113 nt | 0.5597 |
| hsa_OGDH_0003200 | Exon-Exon | chr7:44684926-44733603 | chr7:44645327-44694004 | 1293 nt | 0.5669 |
| hsa_OGDH_0003300 | Exon-Exon | chr7:44684926-44737096 | chr7:44645327-44697497 | 1957 nt | 0.5631 |
| hsa_OGDH_0003400 | Exon-Exon | chr7:44684926-44737381 | chr7:44645327-44697782 | 2136 nt | 0.5655 |
| hsa_OGDH_0003800 | Exon-Exon | chr7:44687043-44714156 | chr7:44647444-44674557 | 509 nt | 0.5285 |
| hsa_OGDH_0003900 | Exon-Exon | chr7:44687256-44687358 | chr7:44647657-44647759 | 103 nt | 0.5437 |
| hsa_OGDH_0004000 | Exon-Exon | chr7:44687256-44706450 | chr7:44647657-44666851 | 219 nt | 0.5616 |
| hsa_OGDH_0004400 | Exon-Exon | chr7:44706335-44721447 | chr7:44666736-44681848 | 818 nt | 0.5501 |
| hsa_OGDH_0004500 | Exon-Exon | chr7:44706335-44741214 | chr7:44666736-44701615 | 2115 nt | 0.5589 |
| hsa_OGDH_0004900 | Exon-Exon | chr7:44713386-44721447 | chr7:44673787-44681848 | 702 nt | 0.5456 |
Showing 11 to 20 of 120 entries
Forensic Context
A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.