Basic Information
Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase
OGDC-E1
OGDH2
KGD1
E1k
Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase
Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide)
2-Oxoglutarate Dehydrogenase Complex Component E1
2-Oxoglutarate Dehydrogenase, Mitochondrial
Alpha-KGDH-E1
EC 1.2.4.2
OGDH-E1
HsOGDH
E1o
Oxoglutarate Dehydrogenase (Succinyl-Transferring)
Alpha-Ketoglutarate Dehydrogenase
Testicular Tissue Protein Li 131
Oxoglutarate Decarboxylase
AKGDH
OGDHD
OGDC
Location (GRCh37)
7:44654708-44748474
UCSC Genome Browser
Location (GRCh38)
7:44615109-44708875
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_OGDH_0005700 | Exon-Exon | chr7:44714010-44714867 | chr7:44674411-44675268 | 238 nt | 0.5210 |
| hsa_OGDH_0005800 | Exon-Exon | chr7:44714010-44715748 | chr7:44674411-44676149 | 418 nt | 0.5359 |
| hsa_OGDH_0005900 | Exon-Exon | chr7:44714010-44721447 | chr7:44674411-44681848 | 547 nt | 0.5430 |
| hsa_OGDH_0006000 | Exon-Exon | chr7:44714010-44733603 | chr7:44674411-44694004 | 727 nt | 0.5598 |
| hsa_OGDH_0006100 | Exon-Exon | chr7:44714010-44734175 | chr7:44674411-44694576 | 880 nt | 0.5614 |
| hsa_OGDH_0006600 | Exon-Exon | chr7:44715569-44737862 | chr7:44675970-44698263 | 1404 nt | 0.5705 |
| hsa_OGDH_0006700 | Exon-Exon | chr7:44715569-44741214 | chr7:44675970-44701615 | 1606 nt | 0.5635 |
| hsa_OGDH_0007400 | Exon-Exon | chr7:44733424-44733603 | chr7:44693825-44694004 | 180 nt | 0.6111 |
| hsa_OGDH_0007500 | Exon-Exon | chr7:44733424-44734175 | chr7:44693825-44694576 | 333 nt | 0.5916 |
| hsa_OGDH_0007600 | Exon-Exon | chr7:44733424-44736663 | chr7:44693825-44697064 | 716 nt | 0.5670 |
Showing 21 to 30 of 120 entries
Forensic Context
A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.