Basic Information
Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase
OGDC-E1
OGDH2
KGD1
E1k
Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase
Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide)
2-Oxoglutarate Dehydrogenase Complex Component E1
2-Oxoglutarate Dehydrogenase, Mitochondrial
Alpha-KGDH-E1
EC 1.2.4.2
OGDH-E1
HsOGDH
E1o
Oxoglutarate Dehydrogenase (Succinyl-Transferring)
Alpha-Ketoglutarate Dehydrogenase
Testicular Tissue Protein Li 131
Oxoglutarate Decarboxylase
AKGDH
OGDHD
OGDC
Location (GRCh37)
7:44654708-44748474
UCSC Genome Browser
Location (GRCh38)
7:44615109-44708875
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_OGDH_0007700 | Exon-Exon | chr7:44733424-44741214 | chr7:44693825-44701615 | 1297 nt | 0.5644 |
| hsa_OGDH_0008100 | Exon-Exon | chr7:44734023-44736663 | chr7:44694424-44697064 | 536 nt | 0.5522 |
| hsa_OGDH_0008700 | Exon-Exon | chr7:44737791-44741214 | chr7:44698192-44701615 | 274 nt | 0.5365 |
| hsa_OGDH_0008800 | Exon-Exon | chr7:44739740-44741214 | chr7:44700141-44701615 | 202 nt | 0.5149 |
| hsa_OGDH_0000100 | Intron-Intron | chr7:44654708-44655310 | chr7:44615109-44615711 | 603 nt | 0.4876 |
| hsa_OGDH_0000300 | Intron-Exon-Intron | chr7:44658423-44664164 | chr7:44618824-44624565 | 364 nt | 0.4835 |
| hsa_OGDH_0000200 | Intron-Exon-Intron | chr7:44658423-44664866 | chr7:44618824-44625267 | 250 nt | 0.4520 |
| hsa_OGDH_0000400 | Intron-Exon-Intron | chr7:44661379-44663339 | chr7:44621780-44623740 | 1961 nt | 0.4136 |
| hsa_OGDH_0000500 | Exon-Exon | chr7:44662405-44664164 | chr7:44622806-44624565 | 319 nt | 0.4577 |
| hsa_OGDH_0000900 | Exon-Exon | chr7:44663916-44664164 | chr7:44624317-44624565 | 249 nt | 0.4498 |
Showing 31 to 40 of 120 entries
Forensic Context
A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.