Basic Information
Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase
OGDC-E1
OGDH2
KGD1
E1k
Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase
Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide)
2-Oxoglutarate Dehydrogenase Complex Component E1
2-Oxoglutarate Dehydrogenase, Mitochondrial
Alpha-KGDH-E1
EC 1.2.4.2
OGDH-E1
HsOGDH
E1o
Oxoglutarate Dehydrogenase (Succinyl-Transferring)
Alpha-Ketoglutarate Dehydrogenase
Testicular Tissue Protein Li 131
Oxoglutarate Decarboxylase
AKGDH
OGDHD
OGDC
Location (GRCh37)
7:44654708-44748474
UCSC Genome Browser
Location (GRCh38)
7:44615109-44708875
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr7_0418200 | Intergenic-Intergenic | chr7:44664008-44684997 | chr7:44624409-44645398 | 157 nt | 0.4650 |
| hsa_chr7_0418300 | Intergenic-Intergenic | chr7:44672191-44674017 | chr7:44632592-44634418 | 1827 nt | 0.4948 |
| hsa_chr7_0418400 | Intergenic-Intergenic | chr7:44679705-44680200 | chr7:44640106-44640601 | 496 nt | 0.4214 |
| hsa_OGDH_0002100 | Intron-Exon-Intron | chr7:44681921-44688943 | chr7:44642322-44649344 | 250 nt | 0.4280 |
| hsa_OGDH_0002200 | Intron-Exon-Intron | chr7:44682115-44687133 | chr7:44642516-44647534 | 91 nt | 0.4176 |
| hsa_OGDH_0002900 | Exon-Exon | chr7:44684926-44713540 | chr7:44645327-44673941 | 155 nt | 0.5548 |
| hsa_OGDH_0003000 | Exon-Exon | chr7:44684926-44715748 | chr7:44645327-44676149 | 87 nt | 0.4023 |
| hsa_chr7_0418500 | Intergenic-Intergenic | chr7:44684983-44713433 | chr7:44645384-44673834 | 344 nt | 0.5640 |
| hsa_OGDH_0003500 | Exon-Exon | chr7:44684986-44713540 | chr7:44645387-44673941 | 539 nt | 0.5436 |
| hsa_OGDH_0003600 | Exon-Exon | chr7:44685070-44706369 | chr7:44645471-44666770 | 186 nt | 0.5591 |
Showing 51 to 60 of 120 entries
Forensic Context
A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.