Basic Information

Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase OGDC-E1 OGDH2 KGD1 E1k Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide) 2-Oxoglutarate Dehydrogenase Complex Component E1 2-Oxoglutarate Dehydrogenase, Mitochondrial Alpha-KGDH-E1 EC 1.2.4.2 OGDH-E1 HsOGDH E1o Oxoglutarate Dehydrogenase (Succinyl-Transferring) Alpha-Ketoglutarate Dehydrogenase Testicular Tissue Protein Li 131 Oxoglutarate Decarboxylase AKGDH OGDHD OGDC
Location (GRCh37)
7:44654708-44748474 UCSC Genome Browser
Location (GRCh38)
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr7_0418600 Intergenic-Intergenic chr7:44685085-44713433 chr7:44645486-44673834 81 nt 0.5185
hsa_OGDH_0003700 Exon-Exon chr7:44687043-44706450 chr7:44647444-44666851 136 nt 0.4191
hsa_OGDH_0004100 Exon-Exon chr7:44687256-44721447 chr7:44647657-44681848 232 nt 0.5560
hsa_chr7_0418700 Intergenic-Intergenic chr7:44693536-44707957 chr7:44653937-44668358 250 nt 0.3640
hsa_OGDH_0004200 Intron-Exon chr7:44694175-44715748 chr7:44654576-44676149 250 nt 0.4560
hsa_chr7_0418800 Intergenic-Intergenic chr7:44699838-44700409 chr7:44660239-44660810 572 nt 0.4161
hsa_OGDH_0004300 Intron-Exon-Intron chr7:44705456-44706450 chr7:44665857-44666851 995 nt 0.4462
hsa_OGDH_0004600 Exon-Exon chr7:44706335-44713540 chr7:44666736-44673941 271 nt 0.5646
hsa_OGDH_0004700 Exon-Exon chr7:44706335-44715748 chr7:44666736-44676149 91 nt 0.5055
hsa_OGDH_0004800 Exon-Exon chr7:44706370-44715748 chr7:44666771-44676149 180 nt 0.5556
Showing 61 to 70 of 120 entries
Forensic Context

A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.