Basic Information
Symbol
circOGDH
RNA Class
circRNA
Alias
Oxoglutarate Dehydrogenase
OGDC-E1
OGDH2
KGD1
E1k
Thiamine Diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase
Oxoglutarate (Alpha-Ketoglutarate) Dehydrogenase (Lipoamide)
2-Oxoglutarate Dehydrogenase Complex Component E1
2-Oxoglutarate Dehydrogenase, Mitochondrial
Alpha-KGDH-E1
EC 1.2.4.2
OGDH-E1
HsOGDH
E1o
Oxoglutarate Dehydrogenase (Succinyl-Transferring)
Alpha-Ketoglutarate Dehydrogenase
Testicular Tissue Protein Li 131
Oxoglutarate Decarboxylase
AKGDH
OGDHD
OGDC
Location (GRCh37)
7:44654708-44748474
UCSC Genome Browser
Location (GRCh38)
7:44615109-44708875
Host gene
OGDH
Host category
mRNA
Forensic tag(s)
Postmortem interval inference
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_OGDH_0005500 | Intron-Exon-Intron | chr7:44713989-44714867 | chr7:44674390-44675268 | 259 nt | 0.5290 |
| hsa_OGDH_0005600 | Intron-Exon-Intron | chr7:44713989-44721447 | chr7:44674390-44681848 | 568 nt | 0.5458 |
| hsa_OGDH_0006200 | Exon-Exon | chr7:44714010-44737862 | chr7:44674411-44698263 | 147 nt | 0.5306 |
| hsa_OGDH_0006300 | Exon-Exon | chr7:44714063-44734175 | chr7:44674464-44694576 | 827 nt | 0.5635 |
| hsa_OGDH_0006400 | Exon-Exon | chr7:44714777-44715748 | chr7:44675178-44676149 | 271 nt | 0.5387 |
| hsa_OGDH_0006500 | Exon-Exon | chr7:44714777-44721447 | chr7:44675178-44681848 | 400 nt | 0.5475 |
| hsa_OGDH_0006800 | Exon-Exon | chr7:44715569-44721447 | chr7:44675970-44681848 | 309 nt | 0.5599 |
| hsa_OGDH_0006900 | Exon-Exon | chr7:44715569-44736156 | chr7:44675970-44696557 | 180 nt | 0.5556 |
| hsa_OGDH_0007000 | Intron-Intron | chr7:44717045-44720062 | chr7:44677446-44680463 | 250 nt | 0.3880 |
| hsa_OGDH_0007100 | Exon-Exon | chr7:44721319-44739868 | chr7:44681720-44700269 | 72 nt | 0.5972 |
Showing 81 to 90 of 120 entries
Forensic Context
A study in mice demonstrated that the linear and circular RNA form of the circOGDH (LC-Ogdh) was evaluated as a reference gene for postmortem interval (PMI) estimation in liver tissue, where it was identified as the most stable candidate using geNorm and NormFinder algorithms [Tu et al. DOI:10.1007/s12024-018-9973-y]. The research, which examined RNA degradation in heart, liver, and skeletal muscle over eight days postmortem, found that LC-Ogdh showed prioritized stability in liver, ranking first among the tested genes, and was part of a tissue-specific panel of stable reference genes for normalization in RT-qPCR-based PMI estimation.