Basic Information
Symbol
circPHLPP2
RNA Class
circRNA
Alias
PH Domain And Leucine Rich Repeat Protein Phosphatase 2
KIAA0931
PHLPPL
PPM3B
PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 2
Protein Phosphatase, Mg2+/Mn2+ Dependent 3B
EC 3.1.3.16
PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase-Like
PH Domain And Leucine Rich Repeat Protein Phosphatase-Like
PHLPP-Like
Location (GRCh37)
16:71712658-71715808
UCSC Genome Browser
Location (GRCh38)
16:71678755-71681905
Host gene
PHLPP2
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PHLPP2_0012400 | Exon-Exon | chr16:71712658-71715808 | chr16:71678755-71681905 | 533 nt | 0.4278 |
Forensic Context
A review of literature on circular RNAs (circRNAs) in embryogenesis and cancer development, covering human, mouse, zebrafish, and pig models, synthesizes findings from multiple studies indicating that circRNAs are stable, cell-type-specific molecules with biomarker potential across various diseases [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans demonstrated that the circPHLPP2 is a circular RNA marker for venous blood identification, detectable in most semen samples with low expression, and its minor alleles from non-target body fluids were detectable in mixtures [Yu et al. DOI:10.1016/j.fsigen.2025.103416].