Basic Information
Symbol
circPOMT1
RNA Class
circRNA
Alias
Protein O-Mannosyltransferase 1
LGMD2K
Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1
Protein O-Mannosyl-Transferase 1
EC 2.4.1.109
Dolichyl-Phosphate-Mannose-Protein Mannosyltransferase
Testis Tissue Sperm-Binding Protein Li 57p
EC 2.4.1
LGMDR11
MDDGA1
MDDGB1
MDDGC1
RT
Location (GRCh37)
9:134381501-134381840
UCSC Genome Browser
Location (GRCh38)
9:131506114-131506453
Host gene
POMT1
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_POMT1_0000800 | Exon-Exon | chr9:134381501-134381840 | chr9:131506114-131506453 | 158 nt | 0.4304 |
Forensic Context
A study in mice demonstrated that the circPOMT1 is highly expressed in brain tissue and plays crucial roles in brain development and neurological disorders such as Alzheimer's disease [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery segments from a postmortem case demonstrated that the expression of the circPOMT1 was validated by qRT-PCR and its circular nature was confirmed via Sanger sequencing, showing significant differential expression across arterial segments with varying atherosclerosis severity [Hou et al. DOI:10.1002/jcla.23552].