Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0007300 | Exon-Exon | chr8:68981268-69012078 | chr8:68069033-68099843 | 160 nt | 0.3313 |
| hsa_PREX2_0007000 | Exon-Exon | chr8:68981268-69028167 | chr8:68069033-68115932 | 1987 nt | 0.4172 |
| hsa_PREX2_0007400 | Exon-Exon | chr8:68981268-69033284 | chr8:68069033-68121049 | 110 nt | 0.3273 |
| hsa_PREX2_0007500 | Exon-Exon | chr8:68981268-69050752 | chr8:68069033-68138517 | 110 nt | 0.3273 |
| hsa_PREX2_0006800 | Exon-Exon | chr8:68981268-69069671 | chr8:68069033-68157436 | 250 nt | 0.2880 |
| hsa_PREX2_0007600 | Exon-Exon | chr8:68981268-69104760 | chr8:68069033-68192525 | 191 nt | 0.5550 |
| hsa_PREX2_0007700 | Exon-Exon | chr8:68982070-69002950 | chr8:68069835-68090715 | 807 nt | 0.4139 |
| hsa_PREX2_0007900 | Exon-Exon | chr8:68982070-69009436 | chr8:68069835-68097201 | 384 nt | 0.4323 |
| hsa_PREX2_0007800 | Exon-Exon | chr8:68982070-69012078 | chr8:68069835-68099843 | 1272 nt | 0.4151 |
| hsa_PREX2_0008000 | Exon-Exon | chr8:68984730-69000044 | chr8:68072495-68087809 | 620 nt | 0.3952 |
Showing 91 to 100 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].