Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0008300 | Exon-Exon | chr8:68984730-69002950 | chr8:68072495-68090715 | 137 nt | 0.5182 |
| hsa_PREX2_0008100 | Exon-Exon | chr8:68984730-69009436 | chr8:68072495-68097201 | 1060 nt | 0.4245 |
| hsa_PREX2_0008200 | Exon-Exon | chr8:68984730-69012078 | chr8:68072495-68099843 | 1222 nt | 0.4173 |
| hsa_PREX2_0008700 | Exon-Exon | chr8:68989632-69005957 | chr8:68077397-68093722 | 124 nt | 0.4274 |
| hsa_PREX2_0008600 | Exon-Exon | chr8:68989632-69009436 | chr8:68077397-68097201 | 984 nt | 0.4278 |
| hsa_PREX2_0008800 | Exon-Exon | chr8:68989632-69012078 | chr8:68077397-68099843 | 93 nt | 0.3333 |
| hsa_PREX2_0008900 | Exon-Exon | chr8:68989632-69021747 | chr8:68077397-68109512 | 320 nt | 0.4656 |
| hsa_PREX2_0009000 | Intron-Intron | chr8:68990676-68991218 | chr8:68078441-68078983 | 543 nt | 0.3370 |
| hsa_PREX2_0009100 | Intron-Exon-Intron | chr8:68991751-69002950 | chr8:68079516-68090715 | 223 nt | 0.5112 |
| hsa_PREX2_0009200 | Exon-Exon | chr8:68992678-68993073 | chr8:68080443-68080838 | 236 nt | 0.3347 |
Showing 101 to 110 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].