Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0009300 | Exon-Exon | chr8:68992678-68995623 | chr8:68080443-68083388 | 385 nt | 0.3584 |
| hsa_PREX2_0009400 | Exon-Exon | chr8:68992678-69002950 | chr8:68080443-68090715 | 608 nt | 0.4145 |
| hsa_PREX2_0009600 | Exon-Exon | chr8:68992678-69005957 | chr8:68080443-68093722 | 93 nt | 0.3333 |
| hsa_PREX2_0009500 | Exon-Exon | chr8:68992678-69009436 | chr8:68080443-68097201 | 911 nt | 0.4237 |
| hsa_PREX2_0009700 | Intron-Intron | chr8:68993074-68993859 | chr8:68080839-68081624 | 786 nt | 0.4746 |
| hsa_PREX2_0009800 | Exon-Exon | chr8:68995475-69012078 | chr8:68083240-68099843 | 837 nt | 0.4385 |
| hsa_PREX2_0009900 | Intron-Intron | chr8:68996981-68999480 | chr8:68084746-68087245 | 2500 nt | 0.3496 |
| hsa_PREX2_0010000 | Intron-Intron | chr8:68997097-68999236 | chr8:68084862-68087001 | 2140 nt | 0.3435 |
| hsa_PREX2_0010700 | Exon-Exon | chr8:68999959-69012078 | chr8:68087724-68099843 | 688 nt | 0.4477 |
| hsa_PREX2_0010800 | Exon-Exon | chr8:68999959-69020566 | chr8:68087724-68108331 | 86 nt | 0.5000 |
Showing 111 to 120 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].