Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0010900 | Intron-Exon-Intron | chr8:68999959-69024401 | chr8:68087724-68112166 | 92 nt | 0.5000 |
| hsa_PREX2_0011000 | Exon-Exon | chr8:68999959-69032521 | chr8:68087724-68120286 | 86 nt | 0.5000 |
| hsa_PREX2_0011100 | Exon-Exon | chr8:68999959-69033284 | chr8:68087724-68121049 | 86 nt | 0.5000 |
| hsa_PREX2_0011200 | Exon-Exon | chr8:68999959-69046511 | chr8:68087724-68134276 | 346 nt | 0.4884 |
| hsa_PREX2_0011300 | Exon-Exon | chr8:68999959-69050752 | chr8:68087724-68138517 | 103 nt | 0.3786 |
| hsa_PREX2_0011400 | Exon-Exon | chr8:68999959-69104760 | chr8:68087724-68192525 | 92 nt | 0.5109 |
| hsa_PREX2_0011500 | Exon-Exon | chr8:68999959-69129953 | chr8:68087724-68217718 | 103 nt | 0.5825 |
| hsa_PREX2_0011600 | Exon-Exon | chr8:68999959-69144080 | chr8:68087724-68231845 | 92 nt | 0.4783 |
| hsa_PREX2_0010600 | Exon-Exon | chr8:68999959-69144158 | chr8:68087724-68231923 | 250 nt | 0.3440 |
| hsa_PREX2_0011900 | Exon-Exon | chr8:69002814-69012078 | chr8:68090579-68099843 | 602 nt | 0.4402 |
Showing 121 to 130 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].