Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0012000 | Exon-Exon | chr8:69002814-69021858 | chr8:68090579-68109623 | 1033 nt | 0.4443 |
| hsa_PREX2_0011700 | Exon-Exon | chr8:69002814-69058587 | chr8:68090579-68146352 | 2118 nt | 0.4415 |
| hsa_PREX2_0011800 | Exon-Exon | chr8:69002814-69136861 | chr8:68090579-68224626 | 2662 nt | 0.4557 |
| hsa_PREX2_0012100 | Intron-Intron | chr8:69003676-69003848 | chr8:68091441-68091613 | 173 nt | 0.3873 |
| hsa_PREX2_0012400 | Exon-Exon | chr8:69005840-69009436 | chr8:68093605-68097201 | 303 nt | 0.4422 |
| hsa_PREX2_0012500 | Exon-Exon | chr8:69005840-69020566 | chr8:68093605-68108331 | 118 nt | 0.4237 |
| hsa_PREX2_0012300 | Exon-Exon | chr8:69005840-69069671 | chr8:68093605-68157436 | 2096 nt | 0.4346 |
| hsa_PREX2_0012600 | Exon-Exon | chr8:69005840-69104760 | chr8:68093605-68192525 | 353 nt | 0.4703 |
| hsa_PREX2_0012700 | Exon-Exon | chr8:69005840-69136861 | chr8:68093605-68224626 | 124 nt | 0.4274 |
| hsa_PREX2_0013100 | Exon-Exon | chr8:69009252-69012078 | chr8:68097017-68099843 | 185 nt | 0.4541 |
Showing 131 to 140 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].