Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0013800 | Exon-Exon | chr8:69020344-69039654 | chr8:68108109-68127419 | 42 nt | 0.4286 |
| hsa_PREX2_0013900 | Exon-Exon | chr8:69020344-69104760 | chr8:68108109-68192525 | 414 nt | 0.4831 |
| hsa_chr8_0416800 | Intergenic-Intergenic | chr8:69024190-69024661 | chr8:68111955-68112426 | 472 nt | 0.3792 |
| hsa_PREX2_0014000 | Intron-Exon-Intron | chr8:69026503-69039654 | chr8:68114268-68127419 | 175 nt | 0.3657 |
| hsa_PREX2_0014300 | Exon-Exon | chr8:69027988-69033284 | chr8:68115753-68121049 | 487 nt | 0.4353 |
| hsa_PREX2_0014400 | Exon-Exon | chr8:69027988-69039654 | chr8:68115753-68127419 | 48 nt | 0.4375 |
| hsa_PREX2_0014500 | Exon-Exon | chr8:69027988-69046511 | chr8:68115753-68134276 | 174 nt | 0.4540 |
| hsa_PREX2_0014600 | Exon-Exon | chr8:69027988-69050752 | chr8:68115753-68138517 | 103 nt | 0.3786 |
| hsa_PREX2_0014700 | Exon-Exon | chr8:69027988-69058587 | chr8:68115753-68146352 | 198 nt | 0.4394 |
| hsa_PREX2_0014800 | Exon-Exon | chr8:69027988-69069671 | chr8:68115753-68157436 | 358 nt | 0.3855 |
Showing 151 to 160 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].