Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0014100 | Exon-Exon | chr8:69027988-69104023 | chr8:68115753-68191788 | 1267 nt | 0.4357 |
| hsa_PREX2_0014900 | Exon-Exon | chr8:69027988-69104760 | chr8:68115753-68192525 | 553 nt | 0.4611 |
| hsa_PREX2_0015000 | Exon-Exon | chr8:69027988-69129953 | chr8:68115753-68217718 | 180 nt | 0.4056 |
| hsa_PREX2_0014200 | Exon-Exon | chr8:69027988-69136861 | chr8:68115753-68224626 | 1629 nt | 0.4629 |
| hsa_PREX2_0015100 | Exon-Exon | chr8:69028023-69050752 | chr8:68115788-68138517 | 426 nt | 0.4296 |
| hsa_PREX2_0015200 | Exon-Exon | chr8:69028023-69058587 | chr8:68115788-68146352 | 247 nt | 0.3765 |
| hsa_PREX2_0015300 | Exon-Exon | chr8:69028023-69069671 | chr8:68115788-68157436 | 115 nt | 0.4087 |
| hsa_PREX2_0015400 | Exon-Exon | chr8:69028023-69104760 | chr8:68115788-68192525 | 336 nt | 0.5000 |
| hsa_PREX2_0015500 | Exon-Exon | chr8:69028113-69030879 | chr8:68115878-68118644 | 150 nt | 0.4867 |
| hsa_PREX2_0015900 | Exon-Exon | chr8:69030785-69033284 | chr8:68118550-68121049 | 135 nt | 0.4444 |
Showing 161 to 170 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].