Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0016000 | Exon-Exon | chr8:69030785-69050752 | chr8:68118550-68138517 | 198 nt | 0.4394 |
| hsa_PREX2_0015700 | Exon-Exon | chr8:69030785-69058587 | chr8:68118550-68146352 | 905 nt | 0.4453 |
| hsa_PREX2_0016100 | Exon-Exon | chr8:69030785-69069671 | chr8:68118550-68157436 | 210 nt | 0.4524 |
| hsa_PREX2_0016200 | Exon-Exon | chr8:69030785-69104760 | chr8:68118550-68192525 | 258 nt | 0.5233 |
| hsa_PREX2_0015800 | Exon-Exon | chr8:69030785-69136861 | chr8:68118550-68224626 | 1449 nt | 0.4700 |
| hsa_PREX2_0016300 | Exon-Exon | chr8:69031667-69069671 | chr8:68119432-68157436 | 121 nt | 0.4132 |
| hsa_PREX2_0016400 | Exon-Exon | chr8:69031667-69104760 | chr8:68119432-68192525 | 89 nt | 0.4270 |
| hsa_PREX2_0016500 | Exon-Exon | chr8:69031667-69129953 | chr8:68119432-68217718 | 83 nt | 0.4096 |
| hsa_PREX2_0016600 | Exon-Exon | chr8:69032431-69050752 | chr8:68120196-68138517 | 103 nt | 0.3786 |
| hsa_PREX2_0016700 | Exon-Exon | chr8:69032431-69058587 | chr8:68120196-68146352 | 97 nt | 0.4948 |
Showing 171 to 180 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].