Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0016800 | Exon-Exon | chr8:69032431-69069671 | chr8:68120196-68157436 | 133 nt | 0.4737 |
| hsa_PREX2_0016900 | Exon-Exon | chr8:69033156-69104760 | chr8:68120921-68192525 | 1009 nt | 0.4539 |
| hsa_PREX2_0017100 | Exon-Exon | chr8:69039613-69050752 | chr8:68127378-68138517 | 42 nt | 0.4286 |
| hsa_PREX2_0017200 | Exon-Exon | chr8:69039613-69058587 | chr8:68127378-68146352 | 186 nt | 0.3871 |
| hsa_PREX2_0017300 | Exon-Exon | chr8:69039613-69104760 | chr8:68127378-68192525 | 42 nt | 0.4286 |
| hsa_PREX2_0017400 | Exon-Exon | chr8:69039613-69136861 | chr8:68127378-68224626 | 110 nt | 0.4909 |
| hsa_PREX2_0017900 | Exon-Exon | chr8:69046294-69050752 | chr8:68134059-68138517 | 321 nt | 0.4579 |
| hsa_PREX2_0018000 | Exon-Exon | chr8:69046298-69058587 | chr8:68134063-68146352 | 461 nt | 0.4338 |
| hsa_PREX2_0018100 | Exon-Exon | chr8:69046298-69069671 | chr8:68134063-68157436 | 576 nt | 0.4288 |
| hsa_PREX2_0018200 | Exon-Exon | chr8:69050650-69058587 | chr8:68138415-68146352 | 247 nt | 0.3765 |
Showing 181 to 190 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].