Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0004100 | Exon-Exon | chr8:68942732-68973014 | chr8:68030497-68060779 | 796 nt | 0.4284 |
| hsa_PREX2_0004700 | Exon-Exon | chr8:68950394-68973014 | chr8:68038159-68060779 | 634 nt | 0.4117 |
| hsa_PREX2_0005300 | Exon-Exon | chr8:68956722-68973014 | chr8:68044487-68060779 | 500 nt | 0.4200 |
| hsa_PREX2_0006100 | Exon-Exon | chr8:68968065-69039654 | chr8:68055830-68127419 | 2673 nt | 0.4235 |
| hsa_PREX2_0008400 | Exon-Exon | chr8:68989632-69002950 | chr8:68077397-68090715 | 681 nt | 0.4214 |
| hsa_PREX2_0008500 | Exon-Exon | chr8:68989632-69030879 | chr8:68077397-68118644 | 1852 nt | 0.4298 |
| hsa_PREX2_0010100 | Exon-Exon | chr8:68999959-69005957 | chr8:68087724-68093722 | 341 nt | 0.4809 |
| hsa_PREX2_0010200 | Exon-Exon | chr8:68999959-69009436 | chr8:68087724-68097201 | 526 nt | 0.4715 |
| hsa_PREX2_0010300 | Exon-Exon | chr8:68999959-69021858 | chr8:68087724-68109623 | 1119 nt | 0.4486 |
| hsa_PREX2_0010400 | Exon-Exon | chr8:68999959-69058587 | chr8:68087724-68146352 | 2204 nt | 0.4437 |
Showing 11 to 20 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].