Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0001200 | Exon-Exon | chr8:68930081-68968209 | chr8:68017846-68055974 | 78 nt | 0.3974 |
| hsa_PREX2_0001300 | Exon-Exon | chr8:68930081-68981371 | chr8:68017846-68069136 | 72 nt | 0.3889 |
| hsa_PREX2_0001400 | Exon-Exon | chr8:68930081-69002950 | chr8:68017846-68090715 | 209 nt | 0.4737 |
| hsa_PREX2_0001700 | Exon-Exon | chr8:68931784-68939558 | chr8:68019549-68027323 | 330 nt | 0.3697 |
| hsa_PREX2_0001800 | Exon-Exon | chr8:68931784-68942893 | chr8:68019549-68030658 | 492 nt | 0.4106 |
| hsa_PREX2_0002000 | Exon-Exon | chr8:68931784-68950527 | chr8:68019549-68038292 | 123 nt | 0.3902 |
| hsa_PREX2_0002100 | Exon-Exon | chr8:68931784-68956825 | chr8:68019549-68044590 | 110 nt | 0.5091 |
| hsa_PREX2_0001900 | Exon-Exon | chr8:68931784-68968209 | chr8:68019549-68055974 | 1025 nt | 0.4078 |
| hsa_PREX2_0002200 | Exon-Exon | chr8:68931784-68973014 | chr8:68019549-68060779 | 224 nt | 0.4152 |
| hsa_PREX2_0002800 | Exon-Exon | chr8:68934271-68968115 | chr8:68022036-68055880 | 808 nt | 0.4146 |
Showing 41 to 50 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].