Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0003100 | Exon-Exon | chr8:68934271-68968209 | chr8:68022036-68055974 | 111 nt | 0.3243 |
| hsa_PREX2_0002900 | Intron-Exon-Intron | chr8:68934271-68973434 | chr8:68022036-68061199 | 1423 nt | 0.4097 |
| hsa_PREX2_0003000 | Exon-Exon | chr8:68934271-68995623 | chr8:68022036-68083388 | 1691 nt | 0.3956 |
| hsa_PREX2_0003200 | Exon-Exon | chr8:68934271-69002950 | chr8:68022036-68090715 | 213 nt | 0.3615 |
| hsa_PREX2_0002600 | Exon-Exon | chr8:68934271-69012078 | chr8:68022036-68099843 | 2379 nt | 0.4107 |
| hsa_PREX2_0002700 | Exon-Exon | chr8:68934271-69033284 | chr8:68022036-68121049 | 250 nt | 0.3120 |
| hsa_PREX2_0003300 | Exon-Exon | chr8:68934275-68973014 | chr8:68022040-68060779 | 999 nt | 0.4144 |
| hsa_PREX2_0003500 | Exon-Exon | chr8:68939457-68942893 | chr8:68027222-68030658 | 264 nt | 0.4583 |
| hsa_PREX2_0003800 | Exon-Exon | chr8:68939457-68950527 | chr8:68027222-68038292 | 140 nt | 0.3857 |
| hsa_PREX2_0003900 | Exon-Exon | chr8:68939457-68968209 | chr8:68027222-68055974 | 102 nt | 0.4020 |
Showing 51 to 60 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].