Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PREX2_0005100 | Exon-Exon | chr8:68950394-68982119 | chr8:68038159-68069884 | 50 nt | 0.3600 |
| hsa_PREX2_0004800 | Exon-Exon | chr8:68950394-68984805 | chr8:68038159-68072570 | 864 nt | 0.3958 |
| hsa_PREX2_0005200 | Intron-Exon-Intron | chr8:68956688-68973014 | chr8:68044453-68060779 | 101 nt | 0.4455 |
| hsa_PREX2_0005500 | Intron-Exon-Intron | chr8:68956722-68973434 | chr8:68044487-68061199 | 104 nt | 0.5192 |
| hsa_PREX2_0005400 | Exon-Exon | chr8:68956722-69129953 | chr8:68044487-68217718 | 250 nt | 0.4360 |
| hsa_PREX2_0005600 | Intron-Intron | chr8:68962469-68963098 | chr8:68050234-68050863 | 630 nt | 0.4492 |
| hsa_PREX2_0005700 | Exon-Exon | chr8:68965332-68968209 | chr8:68053097-68055974 | 295 nt | 0.3763 |
| hsa_PREX2_0005900 | Exon-Exon | chr8:68965332-68973014 | chr8:68053097-68060779 | 150 nt | 0.3667 |
| hsa_PREX2_0005800 | Exon-Exon | chr8:68965332-69002950 | chr8:68053097-68090715 | 1307 nt | 0.4009 |
| hsa_PREX2_0006000 | Exon-Exon | chr8:68965332-69104760 | chr8:68053097-68192525 | 150 nt | 0.3667 |
Showing 71 to 80 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].