Basic Information
Symbol
circPREX2
RNA Class
circRNA
Alias
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2
PPP1R129
P-REX2
DEPDC2
DEP.2
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Protein Phosphatase 1, Regulatory Subunit 129
PtdIns(3,4,5)-Dependent Rac Exchanger 2
DEP Domain-Containing Protein 2
FLJ12987
Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 2
DEP Domain Containing 2
P-Rex2
Location (GRCh37)
8:68879396-69144158
UCSC Genome Browser
Location (GRCh38)
8:67967161-68231923
Host gene
PREX2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr8_0416600 | Intergenic-Intergenic | chr8:68965425-68968190 | chr8:68053190-68055955 | 183 nt | 0.3934 |
| hsa_PREX2_0006200 | Exon-Exon | chr8:68968065-68973014 | chr8:68055830-68060779 | 246 nt | 0.4106 |
| hsa_PREX2_0006300 | Exon-Exon | chr8:68968065-68984805 | chr8:68055830-68072570 | 476 nt | 0.3824 |
| hsa_PREX2_0006400 | Exon-Exon | chr8:68972914-68984805 | chr8:68060679-68072570 | 331 nt | 0.3807 |
| hsa_PREX2_0006500 | Exon-Exon | chr8:68972914-68989704 | chr8:68060679-68077469 | 79 nt | 0.4684 |
| hsa_PREX2_0006600 | Exon-Exon | chr8:68972914-69012078 | chr8:68060679-68099843 | 101 nt | 0.4455 |
| hsa_PREX2_0006700 | Exon-Exon | chr8:68972914-69039654 | chr8:68060679-68127419 | 42 nt | 0.4286 |
| hsa_PREX2_0007100 | Exon-Exon | chr8:68981268-68995623 | chr8:68069033-68083388 | 253 nt | 0.3676 |
| hsa_PREX2_0007200 | Exon-Exon | chr8:68981268-69002950 | chr8:68069033-68090715 | 110 nt | 0.3364 |
| hsa_PREX2_0006900 | Exon-Exon | chr8:68981268-69005957 | chr8:68069033-68093722 | 1029 nt | 0.4062 |
Showing 81 to 90 of 197 entries
Forensic Context
A study in rats demonstrated that heroin self-administration significantly regulated orbitofrontal cortex circular RNAs, with microarray analysis identifying 76 candidates; subsequent qPCR validation in biological replicates confirmed several heroin-responsive circRNAs, though the circPREX2 was identified in the initial screen but did not show significant regulation in validation assays in male or female rats after heroin [Floris et al. DOI:10.3390/ijms23031453].